Antazoline is a drug called an antihistamine that works against allergic reactions. It is mostly used in combination with a sympathetic stimulating drug. Antazoline is mainly used as eye drops for allergic conjunctivitis, which e.g. when hay fever can occur.
Read more on the subject at: Antihistamines
The messenger substance histamine is increasingly released from mast cells, especially in the case of inflammatory processes and allergies. Mast cells are white blood cells and are part of the body's defenses. After binding to various docking sites, so-called histamine receptors, on surrounding cells, it occurs typical allergic reactions.
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These are expressed, for example, in the expansion of the vessels, which leads to increased blood flow and thus leads to heating and flushing of the respective area. Furthermore, the permeability of the vessels increases, the flow of tears increases Eyes swell and itch.
Antazoline also binds to certain histamine receptors (H1), but without triggering a response. The Binding sites for histamine are then blocked and the allergic reaction is stopped.
Since antazoline is mainly used as an eye drop only on the affected area, most of the active ingredient does not get into the bloodstream. That's why it comes very rarely to side effects outside the affected area and the drug is generally very well tolerated.
In the eye there can be one irritation, or one Hypersensitivity reaction, combined with a burning sensation in the eye.
The most common side effects occur with combined active ingredients such as tetryzoline. There are above all dry eyes, blurred vision, and a dilated pupil noticeable.
$config[ads_text2] not foundIf you have a previous illness of green stars should use these eye drops not applied as it can lead to an acute attack.
The drug should also not in children under 2 years of age be used.
The most common form of application of antazoline are eye drops, which are especially useful for a allergic conjunctivitis can be used. The lower eyelid is pulled forward slightly and the eye drops are dripped directly into the conjunctival sac. Care should be taken to ensure that the tip of the dropper does not come into contact with the eye. To avoid further eye irritation and contamination of both the eye and the dropper. Since the mucous membrane is very thin and well supplied with blood at this point, the Active ingredient absorbed quickly become. This leads to a rapid onset of action.
The eye drops usually consist of one Combination of two active ingredients. In most cases, these are antazoline with antiallergic effects and Tetryzoline with symathomimetic effect.
The abbreviation HCL stands for Hydrochloride (or hydrogen chloride) and is better under the name hydrochloric acid known.
In their chemical structure, many drugs are present as bases. In order to make them more soluble in water, acids are added and used as hydrochlorides. This allows drugs such as eye drops to be converted into a liquid form as an aqueous solution. After that the substances are called in this case e.g. no longer just tetryzoline, but tetryzoline hydrochloride. This is how the Improved administrability and stability of the drugs.
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The active substance Tetryzoline, is a so called Sympathomimeticwhich, as the name suggests, imitates the action of the sympathetic nervous system. Tetryzoline binds to certain sympathetic receptors, which among other things makes it a Narrowing of the vessels in the eye comes. This leads to reduced blood flow, decreased redness and a decrease in the flow of tears. The eye swells and conjunctivitis symptoms are relieved.
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