BELOC ZOK MITE

Active ingredient

Belok Zok Mite belongs to the group of beta blockers and is among others used to treat high blood pressure.

Metoprolol

General

Beloc Zok Mite® contains the active ingredient metoprolol in a dose of 47.5 mg. Further doses are 95 mg (Beloc Zok®) and 190 mg (Beloc Zok forte®).
The drug is a so-called sustained release preparation, which means that the active ingredient is released in the body with a delay. On the one hand the effect lasts longer, on the other hand the occurrence of sudden very high drug concentrations is avoided, which in turn reduces the risk of side effects.
Metoprolol belongs to the group of beta blockers. It is widely used in the treatment of cardiovascular diseases but also for the preventive treatment of migraines (migraine prophylaxis).
Metoprolol is one of the most frequently used beta blockers in Germany.

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Read more about this under: Metoprolol

Application and indication

Belok Zok Mite® is used to treat high blood pressure (arterial hypertension), coronary artery disease (KHK), tachycardiac arrhythmias (i.e. cardiac arrhythmias in which the heart beats too fast), chronic compensated (i.e. more stable) Heart failure, functional heart problems and for Migraine prophylaxis.
Beta blockers reduce mortality after acute myocardial infarction and are used here at an early stage, provided the patient is stable. Also in the Reinfarction prophylaxis after a heart attack they play an important role and are used by default, provided there are no contraindications.

Dosage of Beloc Zok Mite®

The dose depends on the disease being treated with Beloc Zok Mite®.

At high blood pressure, coronary artery disease and functional heart disease the usual daily dose is included 50-100 mg Metoprolol, taken in 1-2 single doses. The maximum daily dose is 200 mg.
At Cardiac arrhythmias, to Reinfarction prophylaxis as well as for Migraine prophylaxis daily doses are between 100 and 200 mg administered, again in 1-2 single doses.
At the acute heart attack - provided the patient is stable - at the beginning 5 mg Belok Zok Mite® administered intravenously, this can be repeated every few minutes. The maximum dose is 15 mg intravenously. If the dose is well tolerated, a switch should be made to oral administration in the form of tablets, starting with a dose of 25-50 mg. If this is tolerated, it is increased individually to 100-200 mg within 48 hours.

It is essential to note that therapy with Beloc Zok Mite® not abruptly canceled as it significantly increases the risk of a heart attack or sudden cardiac death.

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Side effects

The following side effects may occur, especially when starting treatment with Belok Zok Mite®:

fatigue, sleep disorders and Nightmares
Dizziness
a headache
confusion
Gastrointestinal complaints how nausea, Vomit and diarrhea
Skin hypersensitivity reactions: Rash, redness, itching
tingle in the limbs (paraesthesia)

Due to the effect on the heart, treatment with Belok Zok Mite® can lead to Drop in blood pressure (Hypotension) come, sometimes up to temporary loss of consciousness (syncope). An excessive Slowing of the heartbeat (Bradycardia), Palpitations (Palpitations) and Conduction disorders at the heart can occur.

Beta blockers can lead to a Increase in blood lipids (Triglycerides) lead and thus the Increase the risk of atherosclerosis.

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At pre-existing Heart failure it can - especially at the beginning of treatment and if the dose is too high - to one Aggravation of heart failure to lead. This is shown by increased water retention in the legs (Lower leg edema) and shortness of breath (Dyspnea).

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Belok Zok Mite® can do one Hypoglycaemia (Hypoglycemia) with pre-existing diabetes mellitus favor and the Warning symptoms (Sweating, trembling, racing heart) disguise. It should therefore only be used cautiously in diabetics and under regular control.

Beta blockers could become one Narrowing of the airways (Bronchoconstriction), this is particularly important in patients with chronic obstructive pulmonary disease. So are beta blockers contraindicated in bronchial asthma.

In patients with Raynaud's Syndrome (Circulatory disorders of the fingers) it can lead to a Worsening of symptoms , therefore Belok Zok Mite® should be used with caution here. The same applies to patients with peripheral arterial disease (PAD, intermittent claudication).

Also at Psoriasis patients (psoriasis) or family members with psoriasis, treatment with Belok Zok Mite® should only be carried out cautiously, as this can promote worsening of existing psoriasis or a new onset of psoriasis.

Interactions

The following drugs may interact with Belok Zok Mite®:

Other antihypertensive agents:
When combining Belok Zok Mite® (like all other beta blockers) with other antihypertensive drugs (e.g. Diuretics (Water tablets), Nitrates, Calcium antagonists) it can become a excessive lowering of blood pressure come, so here should be dosed carefully and controlled.
Medicines used to treat irregular heartbeat:
A combination of Belok Zok Mite® with Calcium channel blockers which also work on the heart (Verapamil and Diltiazem), is contraindicated due to the Risk of cardiac arrhythmias (AV block). For this very reason, the combination of Belok Zok Mite® with other Drugs used to treat irregular heartbeat (Antiarrhythmics, e.g. amiodarone, sotalol) should be done carefully.
Antidiabetic drugs:
When treating Patients with diabetes it should be noted that Belok Zok Mite® in combination with antidiabetic agents Increase the risk of low blood sugar (hypoglycaemia) and the Masking warning symptoms of hypoglycaemia can.
bronchial asthma:
Also in patients with respiratory diseases who are having Beta-2 mimetics to widen the airways (Bronchodilators) Belok Zok Mite® must be used with caution. The reason is that beta blockers - depending on the type - have the effect of the In some cases, significantly weaken drugs to widen the airwaysbecause they block the receptors that these drugs target.
Antidepressants:
A combination of Belok Zok Mite® with MAO inhibitors (Treatment of a depression) can become a excessive increase in blood pressure With Blood pressure crises to lead.
Before one anesthesia It is imperative that the doctor be informed that treatment with Belok Zok Mite® is being carried out, as numerous interactions can occur between beta blockers and narcotics and muscle relaxants.

Contraindications

Absolute contraindications for treatment with Belok Zok Mite® (and other beta blockers) are:

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a known hypersensitivity against this or similar preparations
a too slow heartbeat (Bradycardia) with a heart rate of less than 50 beats per minute
a acute or decompensated (unstable) chronic heart failure
Cardiac arrhythmias in the sense of a 2nd or 3rd degree AV block
bronchial asthma
shock
higher stages of circulatory disorders (e.g. peripheral arterial disease)
a severely decreased blood pressure (Hypotension)

Relative contraindications (use only very carefully and after carefully weighing the benefits and risks) are:

Circulatory disorders in the early stages (e.g. Raynaud's Syndrome)
Diabetes mellitus
chronic obstructive pulmonary disease such as COPD
psoriasis (Psoriasis).

In the case of liver dysfunction, the dose must be adjusted carefully, as Belok Zok Mite® is then excreted less.

In the pregnancy and Lactation Belok Zok Mite® should only be used after carefully weighing the risks and benefits.

Read more on the topic: Medication in Pregnancy and Medication during breastfeeding

costs

On a private prescription, 100 Beloc Zok Mite® tablets (47.5 mg) cost around 27 euros, 100 Beloc-Zok® tablets (95 mg) cost around 31 euros, 100 Beloc Zoc forte® tablets (190 mg) cost around 34 euros. On presentation of a prescription, 100 Beloc Zok Mite® tablets cost around 16 euros, 100 Beloc Zok® tablets cost around 18 euros, 100 Beloc Zoc forte® tablets cost around 20 euros.

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