substance

Nifedipine is a calcium channel blocker of the dihydropyridine group and is used to treat high blood pressure (hypertension) and heartfelt (Angina pectoris) used.

application areas

Nifedipine is used in Germany to treat the essential hypertension (High blood pressure), at High blood pressure crises (hypertensive crises), Heart feeling (Angina pectoris) and the Raynaud's Syndrome.

Side effects

When taking Nifedipine In addition to the desired effect, there may also be other effects that are undesirable. For the drug nifedipine, these include the following Side effects:

  • a headachegeneral weakness, flushing of the face
  • Dyspepsia, (nausea, Feeling of fullness, belching, heartburnretrosternal pain, premature satiety), anorexia, stomach pain, constipation, Flatulence, Vomit
  • Dry mouth
  • Dyspnea (shortness of breath)
  • Malaise, nervousness, sweating, agitation, sleep disorders
  • sleepiness
  • Hypoesthesia (numbness of the skin)
  • Arthralgia (joint pain), muscle cramps
  • fever
  • Weak-sightedness
  • Polyuria (increased urge to urinate)
  • Reflex tachycardia
  • Infertility (sterility) in men

Contraindications

The presence of one or more of the following speaks against your use of nifedipine Risk factors:

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  • cardiogenic shock
  • unstable angina pectorisAngina pectoris
  • more acute Myocardial infarction
  • higher grade Aortic stenosis
  • Taking of Rifampicin
  • pregnancy

Off-label use

If a man takes nifedipine, it becomes Sperm ability to fertilization an egg cell impaired. Which then increased Cholesterol content in the sperm together with a missing enzyme makes it almost impossible for the sperm to penetrate the shell of the egg cell (zona pellucida).

It is currently debated whether nifedipine is used in men Contraceptive (Means to contraception) could be used. After stopping the drug is the Reproduction again possible without restrictions.


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  • Schnheitschirurgie 
  • Drug 
  • Orthopedics-Online 
  • Internal Medicine 
  • Psychology Online 
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