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A rash may also appear as a symptom of dysentery glandular fever, although the disease may exist without the appearance of the skin.

A rash is not a mandatory criterion of existing glandular fever, but occurs in some patients. Overall, however, only five percent of patients with a Pfeiffer's glandular fever are also affected by a concurrent rash.
If the skin rash occurs, it is often similar to the rash that occurs in a rubella infection, but the rash in Pfeiffer's glandular fever is usually much less pronounced.
The expression of the rash may look different, from just small redness to whiplash-like puffiness associated with itching. In part, the oral mucosa and tongue are reddened at the same time.

How do you treat the rash correctly?

An actual therapy against the Pfeiffersche glandular fever or the accompanying rash does not exist. Only to alleviate symptoms can be used, for example, antipyretic or analgesic drugs.

But there is no symptom-relieving treatment against the rash. Theoretically, cortisone preparations could be used in case of excessive itching, but this is not common in practice. It is important that the children or even adults keep a bed rest. Even after the illness subsides no sport should be driven, as it can come in part as part of the disease to a spleen swelling, so there is a risk of splenic rupture.

Duration of the rash

If a rash occurs during the disease, it usually manifests in the first days of the disease. On average, the disease lasts for about three weeks, so that by no later than the rash should have subsided. However, over the three weeks, over weeks to months, increased fatigue and fatigue may persist.

Rash on the face

There is no preferred place for the rash. In principle, all skin areas can be affected, including the face, which is then dotted with small red dots. At the same time, however, most of the arms, legs and chest are affected.

Rash in the mouth

With the Pfeifferschen glandular fever it can come in rare cases to a Enanthem on the hard palate. It is a rash of the palate. This is also called " petechial", because it is the rash to very small, red dots. In addition, a rash may occur on the trunk of the body, which manifests itself as fine, red spots.
Much more common are grayish deposits of the tonsils, which are very clear when looking at the throat. Their appearance is often referred to as dirty. Other rashes in the mouth, however, are not typical of the Pfeiffer's glandular fever.

Rash after antibiotics

For therapy antibiotics are not suitable in a Pfeifferschen glandular fever, as antibiotics only act against bacterial infections and the Pfeiffer's glandular fever by a virus, the Epstein-Barr virus is triggered.
A rash in a Pfeiffer's glandular fever need not always be triggered by the disease itself, but may also be provoked by the administration of the antibiotic amoxicillin, which was mistakenly prescribed by the doctor, as the Pfeiffer's glandular fever was not recognized as such by the doctor.
This so-called drug eruption is much more pronounced than the rash, which is triggered by a glandular fever. The rash caused by the antibiotic Amoxicillin is intensely red and distributed over the body over a wide area.
If this drug eruption after Ampicillin on, is practically the diagnosis of an existing Pfeiffer's glandular fever made.

Rash after amoxicillin in glandular fever

Amoxicillin is an antibiotic in the beta-lactam group, or more precisely, aminopenicillin. It is used in many diseases caused by bacteria. These include, for example, middle ear infections, urinary tract infections and respiratory tract infections. As an undesirable side effect of amoxicillin treatment, a drug rash, a skin rash, can occur that has very different appearances. Frequently there are rashes or scarlet rashes of the skin that occur about 7 to 12 days after taking the drug.

With the Pfeifferschen glandular fever it comes after the taking of Amoxicillin almost always to a drug eruption. A confusion of Pfeiffer's glandular fever with a bacterial acute tonsillitis may result in amoxicillin being mistakenly given. If a rash occurs, the drug should be discontinued immediately. Even after stopping the antibiotic, the rash may persist for several days and cause severe itching. It is advisable to consult a doctor if such symptoms occur. This type of rash is not a "true" allergy, which is why amoxicillin can be used to treat another condition even if such a rash occurs.

Rash on the tongue

The rash of Pfeiffer's glandular fever spreads throughout the body. Here also the mucous membrane in the mouth area and the tongue is no exception.

The rash on the tongue can be recognized by small blisters and can further restrict swallowing, which is already limited by tonsillitis. The rash is more common in adults than in children, as the whole disease is more harmless in childhood.

Rash on the hand

Viral diseases can also lead to skin rashes on the hands. The inside of the hands is relatively rarely affected, but rashes on the hands can also occur in the Pfeiffer's glandular fever.

Differential diagnosis should also be considered in case of a rash of the palm of the hand-mouth-foot disease. On the hands are often no typical redness recognizable, but rather small bubbles.

Accompanying symptoms


As with many diseases caused by viruses, it can also lead to a rash in the Pfeiffer's glandular fever. This shows in the form of itchy redness and wheals. The itching can be limited by thorough skin care.

Patients should not scratch the skin despite the itching. In the differential diagnosis, an itchy rash should also be thought of as having an allergic reaction to drugs or other viral diseases. Even after healing, the skin may itch even further as it may become dehydrated and flaky.


The Epstein-Barr virus, which triggers the Pfeiffer's glandular fever, belongs to the herpesviruses. The rash may resemble a smallpox rash or cold sore with mild pustules.

The pustules may itch and burn after scratching. The rash can also be similar to other diseases. The pustules are often fluid-filled and become crusty on healing. The contents of the pustules are highly contagious, so contact with others should be restricted.

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How contagious is Pfeiffer's glandular fever?

The time between infection and onset of the disease is between 10 and 50 days. This time, which the virus needs to infect the body, is called incubation time. The transmission of the virus takes place via salivary contact, as the virus is excreted via the saliva.
Even before the first symptoms appear, the disease is already contagious, since the virus is already in the saliva and can therefore be transmitted via a droplet infection. A risk of infection can go beyond the acute illness for a long time. In general, there is a risk of infection over a few months, but sometimes over years. If you are already suffering from glandular fever, you will be immune in the future.

How long a risk of infection in Pfeiffer's glandular fever, can not be said clearly. The virus survives after infection for life in the body of an infected person and is also periodically released into the saliva. The patients are theoretically contagious.
Since almost the entire population over the age of 30 has come into contact with the virus, the risk of infection plays no role for them. In any case, there is an increased risk of infection during an infection and a few weeks after an infection, because in the meantime a lot of the virus is excreted into the saliva, so that infection is easier.
However, contact with an infected person, such as kissing, must be established in order to be infected with glandular fever. Since the infection takes place only via salivary contact, no risk of infection arises from the partially occurring rash itself.

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