Cortisone is a cholesterol-derived messenger that is included in the group of steroid hormones. In fact, it is one of the glucocorticoids, a specific subgroup of steroid hormones.
The cortisone, which is often administered as a drug, is basically just the inactive form of the cortisol produced by the organism itself, but it can not have any effect in this chemical structure.
This fact can be explained by the fact that the cortisone itself is not able to bind to the body cell.
For this reason, the application on the skin makes little sense, taken orally or administered via the vein, however, the molecule can be converted enzymatically into the active form cortisol.
In prolonged stress situations, cortisol is increasingly produced and released into the bloodstream.
It has a similar effect in this context as adrenaline and norepinephrine, which occurs only with a time delay.
Cortisone has an anti-allergic and decongestant effect on the nasal mucosa.
Especially with allergic reactions and special nasal diseases, cortisone-containing nasal sprays are used. A very common application is hay fever or other forms of allergy (house dust, animal hair, etc.)
How often the cortisone nasal spray should be used daily must be determined by the treating physician.
A separate overdose should be avoided.
If a patient suffers from allergic reactions, it is usually necessary to use the nasal spray once a day, preferably in the morning or in the evening. In nasal diseases, the drug is used up to 2 times a day. A triple application may be necessary in the course of serious illnesses and / or surgery, it is then recommended to use the drug in the morning, at noon and in the evening.
In addition to the correct dosage, of course, an ideal application plays a decisive role in the success of the treatment. Only when the cortisone nasal spray reaches all the areas of the nose that require treatment can it be fully effective. This has the consequence that the spray should be introduced as deep as possible in the nose.
Sometimes (for example, with a blocked nose), it is not easy to spray the drug unhindered. In such cases, co-administration of decongestant nasal sprays such as Nasivin, Nasic® or Otriven may help to make the inside of the nose more accessible. The patient should first use a decongestant and only 20 minutes later the cortisone-containing nasal spray. In addition, the spraying in lie is usually more effective.
Cortisone-like active ingredients relieve the symptoms of seasonal, allergic rhinitis (hay fever), as well as in non-seasonal rhinitis due to a house dust allergy.
The active ingredients, which are all related to cortisone, reduce the release of messengers, which play an important role in the allergic reaction. They have an anti-inflammatory effect and relieve the irritation of the nasal mucosa. As a result, they improve symptoms such as sneezing, itching and a runny nose. They continue to act decongestant on the nasal mucosa. However, they damage the nasal mucosa with prolonged use. Furthermore, unlike nasal sprays containing alpha-1 sympathomimetics such as xylometazoline, they do not result in dependence of the nasal mucosa.
Hay fever, which is referred to in the jargon as seasonal allergic rhinitis, affects many people. Due to the pollen in the spring months sufferers suffer from colds and itchy eyes.
There are several medications that can be used to treat hay fever and relieve symptoms. These include nasal sprays with cortisone-like active ingredients. These are intended for short-term use and can relieve the symptoms. However, they do not lead to a cure or to a loss of allergy. Contrary to many claims, nasal sprays containing cortisone-like additives can be used for long-term treatment. However, since hay fever is limited to a certain time window in the year, the treatment with nasal sprays anyway limited in time. However, the allergy should have been detected at least once by a doctor.
In case of intolerance do not use the nasal sprays. The exact nature of the application should be clarified in advance with a doctor, even if you receive the nasal sprays over the counter in the pharmacy. Thus, application errors are avoided and there is an adequate explanation of possible side effects. The effect of cortisone is usually after about 12 hours and can reach the maximum effect after 48 hours. Therefore, it should be applied regularly, preferably early in the morning. Usually one spray is enough a day.
In case of a cold, the use of cortisone-containing nasal sprays is not recommended. A cold is an infectious disease that is mostly caused by viruses and only in rare cases by bacteria. In the treatment of runny nose sprays are used with other additives, such as xylometazoline. Nasal sprays containing this active substance, which belongs to the group of alpha-1-sympathomimetic drugs, must not be used for longer than three weeks as otherwise the nasal mucosa may become dependent.
Cortisone-containing nasal sprays are not suitable for treatment, as they would even favor infection. Its benefit is the treatment of an allergic event. Therefore, you should refrain from this type of nasal spray in an infectious cold.
The treatment with cortisone nasal spray usually has no significant side effects as a rule and in short-term use, since the active ingredient usually can not penetrate from the nasal mucosa into the bloodstream.
In addition, it can be stated that a cortisone-based nasal spray is much gentler on the mucous membranes and thus generally better tolerated than other decongestant sprays (for example Otriven).
Long term and / or overuse may result in side effects. Some patients report dehydration of the nasal mucosa and the occurrence of frequent nosebleeds.
Permanent use of coral-containing nasal sprays is not required in hay fever. The hay fever occurs seasonally and is therefore limited in time. During this time, a continuous use of the nasal spray can take place. For the rest of the year, however, the application would not make sense. People who additionally suffer from a house dust allergy, but may need several times a year to the nasal spray. In principle, a permanent application is possible. Often, there are opinions that claim that cortisone-containing nasal sprays are detrimental to long-term use. However, this is not the case.
In particular, over-the-counter nasal sprays contain very small amounts of active ingredient, which are applied locally. There is hardly any active ingredient in the blood, so that side effects are very rare. The hormone balance is not influenced, unlike a permanent cortisone therapy with tablets. Even with withdrawal symptoms you do not have to be afraid. In rare cases, side effects such as nosebleeds, headaches, sneezing, irritation of the nose and throat, respiratory infections or nasal ulcers may occur. If you experience side effects, it is best to consult your doctor and discuss how to proceed. In case of allergic reactions to the drug, it must be discontinued immediately and a doctor should be consulted.
Nasal sprays containing cortisone-like agents are commonly used to treat seasonal allergic rhinitis (hay fever). These are partly over-the-counter in the pharmacy available. Nevertheless, they should only be used when there is a real need. The hay fever should therefore have been detected at least once by a doctor.
The range of different nasal sprays is large. They are made by different companies and have partly the same composition. However, the proportion of cortisone may also vary. In the following section you will find a selection of nasal sprays with cortisone-like supplements, which you can purchase without prescription at the pharmacy. However, the overview does not claim to be exhaustive, as the supply of medicines also changes from time to time:
1. RATIOALLERG hay fever nasal spray: Contained active substance: beclomethasone dipropionate. For short-term treatment of allergic hay fever. Company: Ratiopharm.
2. MOMETAHEXAL hay fever 50μg: Contains active ingredient: mometasone furoate. For the treatment of allergic hay fever in adults, provided that the initial diagnosis has been made by a doctor. Company: Hexal AG.
3. RHINIVICT nasal 0.05 mg nasal dosing spray: Contained active substance: beclomethasone dipropionate; For short-term treatment of seasonal allergic colds. Company: Dermapharm AG.
4. OTRI allergy nasal spray Fluticasone: Contains active substance: Fluticasone. For use in allergic rhinitis (hay fever). Company: © GlaxoSmithKline Consumer Healthcare GmbH & Co.
5. MOMEALLERG nasal spray 50 μg: Contains active substance: mometasone furoate. For use in allergic rhinitis (hay fever). Company: GALENpharma GmbH
The effectiveness of the pill is limited by various drugs, so that adequate protection may be at risk. A well-known example of this are various antibiotics. However, cortisone and cortisone derivatives do not limit the effectiveness of the pill, so protection is guaranteed. In addition, nasal sprays with cortisone-like active ingredients only act locally on the nasal mucosa anyway, so that systemic impairments and side effects are very unlikely