General

Diovan ® contains the active substance valsartan, which is used to treat high blood pressure and mild to moderate heart failure. Diovan ® belongs to the group of angiotensin 1 antagonists. They are used when ACE inhibitors do not work or are inappropriate. The drug is prescription and the medication should be under the strict supervision of a doctor.

application areas

Diovan ® with the active ingredient valsartan is prescribed by the doctor in the following diseases:

  • Hypertension: mild to moderate blood pressure disorder
  • Heart failure: It can be used in mild to moderate heart failure, as long as ACE inhibitors are unsuitable because of unwanted side effects such as dry cough. If there are side effects associated with the inhibition of the renin-angiotensin-aldosterone system (hyperkalaemia, worsening renal insufficiency) when taking ACE inhibitors, Diovan ® or another valsartan should not be prescribed.
  • Myocardial infarction: After a heart attack Diovan ® can be used as a long-term prophylaxis.

operation

Diovan ® belongs to the group of angiotensin II receptor subtype 1 antagonists. This means; They inhibit angiotensin II, which is an endogenous substance that causes the blood vessels to contract. If this is now inhibited, eliminates the effect of angiotensin II. As a result, expand the blood vessels and the blood pressure drops. This is very important as long term elevated blood pressure will result in consequential damage to the heart and vessels. The risk of heart or kidney failure, stroke or heart attack increases. Diovan ® is also used if so-called ACE inhibitors may not be used or alone bring too little success. If beta-blockers are not suitable for the treatment of heart failure, Valsartane can also be prescribed.

side effects

As with any other medication, the Diovan ® can also cause side effects.
Which includes:

  • skin rash
  • Visual disturbances and pain of the eyeball
  • reduced blood pressure ( hypotension ).

If this decreased blood pressure occurs in conjunction with diuretics, dialysis, diarrhea or vomiting, hypotension can easily lead to circulatory collapse. All these side effects should be reported to a doctor as soon as possible.

In case of imminent kidney disease and sudden accumulation of water in the ankles and legs while taking Diovan ®, consult a doctor immediately.

Contraindications

If one or more of the following applies to you, you should not use Diovan ® !

  • Hypersensitivity to other valsartans such as Angiosan, Cordinate, Provas or Valsacor.
  • Hereditary angioedema: This leads to recurrent swelling (edema) of the skin, mucous membranes and internal organs, which can also be fatal. The edema is usually reddened, painful and often found in the lip area, genitals and extremities.
    If such edema occurred with the use of an ACE inhibitor or an AT1 receptor antagonist, Diovan ® should not be taken.
  • Anuria: less than 100 ml of urine in 24 hours
  • Renal insufficiency: poor kidney function, creatinine clearance <10ml / min

Since there are no reports of Diovan ® in children and adolescents under the age of 18, it is rather discouraged.

Valsartan should not be taken during pregnancy, as experiments on mice showed damage to newborns and even deaths. It has also been shown that Valsartane passes into breast milk, therefore Diovan ® should not be taken during lactation.


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