Olynth®

introduction

Olynth ® is a medication used for swelling of the nasal mucosa, as it has a decongestant effect on the mucous membrane. The nasal mucosa swells in diseases such as runny nose ( rhinitis ), cold and flu-like infections. In addition, there may be an allergic mucosal swelling in the nose. In such cases, the swelling can be treated with Olynth ®, the administration of Olynth ® as a nasal spray, the swelling goes back and the patient can breathe through the nose again.
Furthermore, Olynth ® can facilitate the outflow of secretions in sinusitis and otitis media ( otitis media ) by the general swelling of the mucous membranes.

Olynth ® is suitable for children and adults in various concentrations. Olynth ® can be used as a nasal spray or as a drop.

mechanism of action

Olynth ® is a drug from the class of local sympathomimetics.

The active substance contained in Olynth ® is xylometazoline. This is an active substance in the group of rhinologics (drugs to be used in the nose). Xylometazoline is normally used in salt form as xylometazoline hydrochloride. Olynth ® acts as a sympathomimetic, ie as a substance that positively supports the sympathetic nervous system (part of the autonomic nervous system). In the vessels this means that they contract. This is exactly the desired effect, because the swelling of the nasal mucosa is caused by very relaxed vessels and thereby caused water leakage. By contracting (constriction) of the vessels, no more water can escape, the swelling goes back. Olynth ® has these vasoconstrictive properties because it acts on the alpha receptors present in the vessels.
About five to ten minutes after the application, an improvement in the nasal breathing is already noticeable, in addition, the secretion can drain better.

side effects

Like any drug, Olynth ® may have side effects, but these are rare and are by no means common to any patient. If any side effects occur during use, the treating physician should be informed immediately. This will inform the patient about the risks and decide whether the drug is discontinued or whether it can be taken further.

With the use of Olynth ® occurs with a probability of one to a maximum of ten percent after stopping the effect of increased swelling of the nasal mucosa ( reactive hyperemia ). In less than one percent of cases, Olynth ® causes nosebleeds or sneezing.

With the same frequency effects on the heart occur, such as palpitations and pulse acceleration.
In addition, the blood pressure can rise. In addition, hypersensitivity reactions may occur. These are, for example, a rash or itching or even a reactive swelling of the skin and mucous membrane. In very few cases (less than one patient treated per thousand) headaches may be associated with fatigue and insomnia.

Other side effects that occur in less than one in ten thousand cases are the following. Especially with children, it can lead to illusions, also occur in children heart arrhythmia and cramps. In general, it can come especially during prolonged use to increased burning of the nasal mucosa and dehydration selbiger. These side effects can also be exacerbated by increased dosages. If these symptoms are continued with the use of Olynth ®, permanent damage to the nasal mucosa and the formation of a so-called stink nose with bark formation may occur.

Contraindications

Olynth ® should be avoided if you are known to be allergic or hypersensitive to xylometazoline or any other substance contained in Olynth ® . Here is another ingredient to mention the benzalkonium chloride (a preservative contained in Olynth ® ), this can also trigger hypersensitivity reactions.
If you suffer from the so-called rhinitis sicca (special form of chronic cold), Olynth ® may also not be used. Furthermore, this drug must not be used if a surgical procedure was performed in advance, in which the meninges was exposed. An example is transsphenoidal hypophysectomy, ie the surgical removal of the pituitary gland by the nose.

Careful application

Here you should consult with the treating physician before using Olynth ® :

  • known increased intraocular pressure and especially with known narrow-angle glaucoma
  • High blood pressure ( hypertension ) and other cardiovascular diseases such as coronary heart disease and cardiac arrhythmias
  • other diseases of the vascular system, such as advanced arteriosclerosis and aneurysm
  • Blood pressure enhancing drugs, especially monoamine oxidase inhibitors
  • chronic metabolic diseases, such as diabetes mellitus (diabetes), hyperthyroidism ( hypertrophy ) or porphyria (red blood cell disease (erythrocytes))
  • Patients with pheochromocytoma (an adrenal tumor)
  • Prostate enlargement in older men.

Children need to be taken care of very carefully. For children under the age of two, special Olynth® preparations are available, but the advice of a doctor or pharmacist should be sought. In children, the longer-term use of Olynth ® should be avoided, higher-dose preparations may only be given with the consent of the doctor.

Also with pregnant women special caution is appropriate. Here Olynth ® is actually contraindicated. It should only be used on the advice of the doctor, in special cases.

Care must be taken during pregnancy to ensure that the target dose is maintained, as the blood supply to the unborn child may be impaired by overdose.

Another special case is breast-feeding. While the mother is nursing her baby, it is important to be careful with Olynth® as there are too few studies available and therefore it can not be predicted whether complications will occur. An overdose during breastfeeding must be avoided at all costs as this may affect the mother's milk production.

interactions

It is important to check with your doctor before taking Olynth ® to determine how high the risk is that the medications you are already taking will interact with Olynth ®, resulting in unwanted side effects.

Taking Olynth ® with tricyclic antidepressants, trano-cypromine class monoamine oxidase inhibitors, or general blood pressure boosters may result in an uncontrolled increase in blood pressure. Therefore, it should be avoided to combine these medicines with Olynth ® . On the other hand, no particular foods or drinks need to be omitted when using Olynth® .

taking

Olynth ® is intended for use in the nose (nasal) and should therefore only be used there. The spray bottle is inserted with its tip in succession in both nostrils for use. By briefly pressing the spray bottle, a spray is sprayed into the nostrils, while spraying it should be inhaled lightly through the nose. The application can be done as needed one to three times a day. The effect lasts up to twelve hours, the last application should be followed for a quiet sleep just before bedtime.

In general, there is a risk of infection by spreading the spray bottle to other people. Therefore, the use of each spray bottle is only allowed by one person.

Poisoning with Olynth ®

If you accidentally take too much Olynth ®, you must inform your doctor immediately. Poisonings occur only with considerable overdoses. However, these are difficult to interpret clinical signs, as suppression and stimulation of the cardiovascular system (and the central nervous system) can alternate. When the central nervous system is impaired, it manifests itself in anxiety, arousal and convulsions (stimulation), or drowsiness, lethargy and even coma (inhibition). In addition, symptoms such as fever, paleness, palpitations, respiratory depression to respiratory arrest, nausea and vomiting and narrow ( miosis ) and wide pupils ( mydriasis ) may occur. In the event of poisoning with Olynth ®, the patient must be treated with medical care; admission to a hospital may be necessary.


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