Oxazepam, Adumbran®, Praxiten®
Oxazepam belongs to the benzodiazepine class of drugs. It has a sedative (calming) as well as an anxiolytic (anxiety-relieving) Effect and is used in this sense as a tranquilizer. Tranquilizers are a special class of psychotropic drugs that have an anxiolytic and sedative effect. Oxazepam is an active metabolite of diazepam. A metabolite is a breakdown product of a substance. Diazepam is also a benzodiazepine. Oxazepam itself does not produce any other active metabolites. It belongs to the medium acting bezodiazepines. Its mean duration of action is around 10 hours. This means that it works longer than other benzodiazepines, but also more slowly.
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Oxazepam is usually not prescribed for people who have difficulty falling asleep, but rather it is used for Treatment of difficulty sleeping through the night used. However, due to its anxiolytic and sedative effects, it is also beneficial depressions and Anxiety disorders indexed. In addition, Oxazepam has one muscle relaxant (relaxing the muscle) and a anticonvulsant (antispasmodic) Effect, which is typical for the class of benzodiazepines.
The active ingredient unfolds its effect, like all benzodiazepines, on the so-called GABAa receptor. There he acts as a allosteric activator. This means that oxazepam strengthens the effect of the neurotransmitter GABA on its receptor. GABA is a very important messenger substance in the central nervous system. Oxazepam only works in the presence of the messenger substance GABA and not alone. Ultimately, the activation of this GABAa receptor leads to the Cells of the nervous system less sensitive to stimulating stimuli become. This results in the calming and relaxing effect of oxazepam.
$config[ads_text2] not foundOxazepam will orally taken. The dosage varies depending on the patient's body weight, age and problem.
As a rule, Anxiety disorders and states of excitement no more than three tablets (20-30 mg oxazepam), a maximum of six tablets, taken daily. This information applies to adults.
For children up to 14 years of age, 0.5 - 1 mg / kg body weight is usually given in 3 - 4 single doses a day.
To treat Difficulty sleeping through the night adults usually take a pill (10 mg), maximum three, one.
However, the exact dosage is determined by the doctor and can vary widely.
The maximum duration of intake should 4 weeks do not exceed. The drug should tapered off and not abruptly discontinued become.
The use of oxazepam is contraindicated for the following pre-existing diseases or conditions:
The drug oxazepam can sometimes cause undesirable side effects. These side effects largely correspond to those of the other benzodiazepines. It can too fatigue, Exhaustion and Poor concentration come. In addition, you can Restlessness, Memory problems, Drowsiness and general muscle weakness occur.
Also dizziness, Gastrointestinal disorders and allergic reaction can be caused by oxazepam. An indication of an allergy can be an irritated skin reaction.
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$config[ads_text3] not foundOxazepam should not be used during pregnancy unless clearly necessary contraindicated. The intake of benzodiazepines can lead to respiratory depression, hypotension, hypoactivity and even withdrawal symptoms in the newborn.
