Synonym: somatotropin-inhibitory hormone (SIH)
In addition to insulin and glucagon, somatostatin is a third hormone that is produced in the pancreas (pancreas) will be produced. It is a messenger substance in the human body that mainly inhibits the digestive process. It is also considered an antagonist to numerous other hormones in the body.
Somatostatin is produced in the D cells of the pancreas and released during digestion.
However, it is also produced in many other places in the body:
After the hormone is formed, it is stored in the cells and released when the body is stimulated, for example nerve impulses.
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Read also: Functions of the pancreas
Somatostatin acts as an inhibitor of various hormones such as cortisol, gastrin and secretin. The inhibition of these hormones leads to a decrease in movements in the stomach and intestines, a reduced secretion of digestive juices from the pancreas and an inhibition of the formation of gastric acid.
In addition, it is the antagonist of the growth hormone somatotropin. This is where the name of the hormone (synonym somatotropin-inhibitory hormone (SIH), inhibiting). Somatostatin also inhibits the other two pancreatic hormones, insulin and glucagon.
Synthetically produced somatostatin is used, among other things, to treat diseases such as acromegaly, in which there is an excess of the growth hormone somatotropin.
