Voltaren Resinat® is a drug from the Voltaren product range from the pharmaceutical company Novartis.
It contains the active ingredient diclofenac, which belongs to the group of non-steroidal anti-rheumatics (NSAIDs) and has a pain-relieving and anti-inflammatory effect by inhibiting an enzyme.
This special preparation consists of hard capsules that are available in pack sizes of 20, 50 or 100 capsules. Voltaren Resinat® requires both a pharmacy and a prescription, so it may only be taken after being prescribed by a doctor.
Apart from the active ingredient, which is present here as the salt diclofenac sodium, Voltaren Resinat® contains the auxiliary substances gelatine, medicinal charcoal and magnesium stearate as well as the colorants iron (III) hydroxide oxide and titanium dioxide. Voltaren Resinat® contains the active ingredient diclofenac sodium in a dosage of 75 mg.
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In principle, Voltaren Resinat® is to be used exactly as prescribed by the doctor in terms of frequency and duration of intake. In principle, however, the following guidelines apply:
Depending on the severity of the disease being treated or the pain, a maximum daily dose of 150 mg diclofenac sodium should not be exceeded in adults and adolescents from the age of 15, which is why one should not take more than two tablets of Voltaren Resinat® per day and these on best spread over the day.
The Voltaren Resinat® capsules should be swallowed whole with sufficient liquid. In order to achieve a quick onset of action, it makes sense to take the tablets before a meal. However, if you have a sensitive stomach, you should avoid taking it on an empty stomach and swallow the tablets with food.
If a long-term use of Voltaren Resinat® is planned (as is necessary, for example, in the treatment of rheumatic diseases), it is generally recommended to continue the therapy after two weeks at the latest with enteric drug forms, as these are usually better tolerated . If the pain or the inflammatory conditions do not improve even after regular intake of Voltaren Resinat®, the patient should in any case refrain from increasing the dose on their own, but instead notify a doctor and discuss the further procedure with him.
Voltaren Dispers® is an alternative to Voltaren Resinat®. In comparison to Volatern Resinat®, however, Voltaren Dispers® is dissolved in a glass of water and then drunk. Read detailed information about this under: Voltaren Dispers®
The areas of application recommended by the manufacturer for Voltaren Resinat® include a variety of painful and inflammatory conditions, especially of the musculoskeletal system (to which skeleton, Muscles, Tapes and Tendons are counted).
Voltaren Resinat® is recommended for the treatment of acute or chronic joint inflammation (for example Rheumatoid arthritis), especially if this is due to inflammatory rheumatic diseases or the underlying disease gout are conditional.
Inflammatory diseases of muscles, ligaments or tendons can also be involved Voltaren Resinat® be successfully treated, including, for example, the treatment of the so-called Tennis elbow. For diseases and pain of the Spineregardless of whether they are due to wear and tear (such as arthrosis) or in the context of an inflammatory rheumatic disease (such as ankylosing spondylitis) can occur Voltaren Resinat® can also be used successfully.
This drug is also indicated for mild to moderate pain with inflammation or swelling caused by an operation or an injury. Even with pain in the Menstrual period (Dysmenorrhea), unless they can be explained by an organic finding, or painful inflammation of the Fallopian tubes can be an intake of Voltaren Resinat® (in the latter state, possibly in combination with Antibiotics). To remedy the situation. Also the pain that occurs with some cancers, especially if these are caused by inflammation-related storage of water in the tissue (Edema) go hand in hand or the bone affected, sometimes speak up Voltaren Resinat® on.
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Voltaren resinat®, or the active ingredient Diclofenac, like the others non-steroidal anti-rheumatic drugs (NSAIDs) an enzyme called Cyclooxygenase (COX). Hence these drugs are also called COX inhibitors designated.
Enzymes are biochemical catalysts that have the ability to accelerate biochemical reactions. The enzyme, which is inhibited in its function by Voltaren resinat®, exists in at least two forms in the human organism. One distinguishes the so-called Cyclooxygenase 1 (COX-1) from the Cyclooxygenase 2 (COX-2).
Cyclooxygenase 1 (COX-1) is continuously present in tissues and cells in the same amount and activity, while cyclooxygenase 2 (COX-2) is produced by messenger substances that are present in inflammation (the so-called Inflammation mediators).
In technical terms, it is said that cyclooxygenase 1 (COX-1) constitutively expressed and the cyclooxygenase 2 (COX-2) inducible is. In certain tissues, such as the brain, of the kidney or also the Inner lining of the blood vessels (the Vascular endothelium) however, cyclooxygenase 2 (COX-2) is also continuously present.
Non-steroidal anti-rheumatic drugs (NSAIDs), which also include Voltaren resinat®, ensure one temporary inhibition of activity this enzyme. The inhibition is reversibleThat means it is reversible and after the drug has disappeared the enzyme can continue to work unimpaired.
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In contrast, worry irreversible Enzyme inhibitor so that the enzyme is no longer able to accelerate a biochemical reaction even after the active ingredient has disappeared and must first be re-established in order to be able to perform the function again.
Have different non-steroidal anti-rheumatic drugs (NSAIDs) different effects on the two enzyme forms. So there are active ingredients that more specific for cyclooxygenase 1 (COX-1) or cyclooxygenase 2 (COX-2) or else have the ability both enzymes to limit their effect.
Voltaren resinat® with the active ingredient diclofenac not selective In its effect, i.e. through Voltaren resinat®, both the effect of cyclooxygenase 1 (COX-1) and that of cyclooxygenase 2 (COX-2) are inhibited. This is how the antipyretic (antipyretic), pain reliever (analgesic) and anti-inflammatory (anti-inflammatory) Effect.
The anti-inflammatory effect can be explained by the fact that by inhibiting the cyclooxygenases the Production of messenger substances restricted is that one central role in an inflammatory response take in. These messenger substances include, for example Prostaglandins E2 and I2. Prostaglandins are tissue hormones that are produced by the above-mentioned cyclooxygenases and that have various effects in the human organism, such as the Involvement in inflammatory processes, to have.
Also the analgesic effect runs over the Inhibition of the formation of prostaglandins. That's how it takes care Prostaglandin E2 not even for causing pain, but it is able to Nerve endings for signals that trigger pain to raise awareness. Put simply, prostaglandins usually cause one relieved pain developmentthat is prevented by preparations such as Voltaren resinat®.
The antipyretic effect can also be used with the Prostaglandins E2 explain which one also plays a central role in the fever reaction. Through the Inhibition of the enzymes Voltaren resinat® will do the same inhibited the fever reaction.
In summary it can be said that Volatren resinat® through a Enzyme inhibition the Formation of signal molecules is preventedresponsible for an inflammatory reaction, a fever reaction, and a pain reaction, and so on Signs of inflammation, fever and pain go back.
$config[ads_text1] not foundThe exact time until the onset of action of Voltaren resinat® and the exact duration of action depend individually on the individual person who takes this drug.
The metabolism of the active ingredient diclofenac, which is used in Voltaren resinat®, takes place to a large extent via the liver. Therefore, deteriorated liver function (e.g. caused by excessive alcohol consumption or other liver diseases) lead to a different effective dynamic.
Voltaren resinat® is a drug with a fast-acting and a long-lasting component, a so-called sustained-release preparation. In some cases, the analgesic effect can already be felt after 20 minutes, but in most cases the onset of the effect varies between 45 and 60 minutes.
The effect of Voltaren resinat® can last up to 12 hours in individual cases, but for many users it wears off after 8 to 10 hours. With the prescribed intake of Voltaren resinat® of 1 hard capsule per day or 1 hard capsule in the morning and evening, no depot effect should build up. The drug does not accumulate in the tissue even after prolonged use.
Contraindications to the use of Voltaren dolo exist in the presence of hypersensitivity to Diclofenac or other components of the drug:
Under certain conditions, such as the first few months of pregnancy, during the Lactation, if there is a general tendency to allergic reactions, in patients with autoimmune diseases or if they are taking medications at the same time that have a side-effect profile similar to that of diclofenac (e.g. other NSAIDs how Ibuprofen) or affect the level of diclofenac in the blood (for example some Anti-epileptic drugs how Phenytoin) should stop taking Voltaren Resinat® if at all, then only after consultation and regular monitoring by a doctor.
It should also be used throughout the treatment period Voltaren Resinat® refrain from drinking alcohol.
As with any drug, it can also occur when taking Voltaren Resinat® come to certain side effects.
The enzyme inhibited by diclofenac called Cyclooxygenase is also localized in the gastric mucosa, among other things. There the prostaglandins produced by this enzyme provide protection against the destructive power of gastric acid.
Since the production of these prostaglandins however by Voltaren Resinat®/ If diclofenac is lowered, the balance can be upset and the acid can become harmful.
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Therefore leads Voltaren Resinat® (just like any other cyclooxygenase inhibitor) frequently to side effects in the gastrointestinal area. These include:
If you have severe pain in the upper abdomen or blood in your stool (which then sometimes looks tarry) noticed, you should use the Voltaren Resinat® Stop taking the capsules and see a doctor as soon as possible. Also disturbances of the Central nervous system (CNS) how dizziness, Drowsiness, a headache, fatigue or States of excitement can occur.
Therefore, it is not recommended after taking Voltaren Resinat® to actively participate in road traffic or to operate heavy machinery. The ingestion of Voltaren Resinat® also to hypersensitivity reactions of the body like itch or Rash on the skin. Less often can Voltaren Resinat® also cause other side effects, including among others Hair loss, Disorders of blood formation and blood clotting, kidney or liver damage, psychotic reactions or depressions belong.
Non-steroidal anti-rheumatics (NSAIDs), which include Voltaren resinat®, can be used to treat headaches and migraines.
For adolescents and adults aged 15 and over, a maximum of 150 mg can be taken as the daily maximum dose, this maximum daily dose being divided into two individual doses.
Usually 75 milligrams a day is sufficient.
Paradoxically, high doses of these pain relievers can also induce headaches. This headache is as drug-induced headache known, and is triggered either by the ingestion itself or by withdrawal from certain medications, mostly painkillers.
After International Headache Society (IHS) Classification, this headache represents a subgroup of the substance-induced headache The prerequisite for the development of these symptoms is the presence of a primary headache disorder, such as tension headache or migraine, which makes it necessary to take painkillers.
Drug-induced headache is most commonly observed in middle age and affects women much more frequently with a ratio of 10: 1. It is estimated that 5 to 8% of all headache patients will develop this drug-induced headache.
It is crucial that drug-induced headaches should never be treated with an increased dose of the pain reliever. The only way to successfully treat drug-induced headache in the long term is to withdraw drugs. In addition, headaches can also occur as a symptom of an overdose of Voltaren resinat® in addition to dizziness, drowsiness, unconsciousness and many other symptoms.
Painkillers and alcohol should generally be avoided.
Especially the longer and regular intake of Voltaren resinat® can increasingly lead to a deterioration in liver function. The additional consumption or even abuse of alcohol can possibly lead to increased side effects or further deterioration of the liver.
The gastrointestinal tract and the central nervous system are particularly affected. In the gastrointestinal tract, if Voltaren resinat® and alcohol are taken at the same time, increased nausea and vomiting, as well as digestive disorders and abdominal pain can occur.
In the central nervous system, dizziness, headaches, but also tiredness and dizziness, as well as irritability and loss of appetite can occur.Furthermore, if Voltaren resinat® and alcohol are taken at the same time, kidney dysfunction can worsen further.
A blood-thinning effect and an increase in blood pressure when combining alcohol with Voltaren resinat® are also discussed. It is therefore safest to consistently refrain from consuming alcohol or at least limit it while taking Voltaren resinat®.
